Trintellix (vortioxetine) may not be safe to take while pregnant or breastfeeding. Certain factors, including the risks of not treating your depression during pregnancy, may determine whether you should take Trintellix during this time.
Trintellix may cause harm to a newborn.
Taking this drug during the third trimester of pregnancy could increase the risk of serious lung problems in the newborn. This could lead to them needing breathing support, tube feedings, or hospitalization for longer than usual.
Taking this drug during your third trimester could also cause the newborn to have withdrawal symptoms such as low blood sugar, tremors, and constant crying.
It’s important to keep in mind that stopping treatment with Trintellix if you’re pregnant can also have serious consequences, such as a relapse of major depression.
There is a National Pregnancy Registry for Antidepressants, including Trintellix. This registry collects information about people who take antidepressants during pregnancy and the effects the drugs may have had on infants. If you’re interested in participating in this registry, your doctor can sign you up by calling 844-405-6185 or visiting the website.
If you’re taking Trintellix while pregnant or planning a pregnancy, talk with your doctor. They can provide information about the risks and benefits of starting, continuing, switching, or stopping antidepressants during pregnancy and postpartum.
It’s not known whether Trintellix passes into human breast milk or whether it may affect milk production or a child who is breastfed.
Trintellix was found in the milk of lactating animals exposed to the drug in studies. But animal studies don’t always predict what will happen in humans.
If you’re breastfeeding or considering it, talk with your doctor about the potential risks and benefits of taking Trintellix during this time.
Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.